RU 24969 succinate( RU-24969 | RU24969 | RU 4969 hemisuccinate )

Catalog No. M17135 CAS No. 107008-28-6

COA

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HNMR

HPLC

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Product Name

RU 24969 succinate
Note

Research use only, not for human use.
Brief Description

RU 24969 is a selective agonist at the 5-HT1A and 5-HT1B receptors.
Description

RU-24969 hemisuccinate is a potent serotonin SR-1A/SR-1B and moderate SR-2C agonist.
In Vitro

——
In Vivo

Animal Model:Male Wistar rats with cocaine injection Dosage:1 and 3 mg/kg Administration:Subcutaneous injection; 1 and 3 mg/kg, once Result:Increased cocaine-induced elevation of nucleus accumbens (NAcc) dopamine DA levels and reduction of ventral tegmental area (VTA) GABA levels.
Synonyms

RU-24969 | RU24969 | RU 4969 hemisuccinate
Pathway

Others
Target

Other Targets
Recptor

5-HT1A| 5-HT1B
Research Area

——
Indication

——

CAS Number

107008-28-6
Formula Weight

574.67
Molecular Formula

C32H38N4O6
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 120 mg/mL (346.44 mM)
SMILES

c1(ccc2c(c1)c(c[nH]2)C1=CCNCC1)OC.C(=O)(CCC(=O)O)O.c1(ccc2c(c1)c(c[nH]2)C1=CCNCC1)OC
Chemical Name

5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole hemisuccinate

1. Doods HN, et al. Eur J Pharmacol. 1985 Jun 19;112(3):363-70.2. Green AR, et al. Neuropharmacology. 1984 Jun;23(6):655-61.

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